THANZ Travel Grant Winners

2024 THANZ Travel Grant Winners

• Ibrahim Tohidi-Esfahani (John Lloyd Travel Grant)– RNA Sequencing identifies differential Transcriptomic Signatures in Platelet subpopulations and the proximal role of large GTPase dynamin in Procoagulant Platelet Formation
• Vijay Bhoopalan– Ribosome biogenesis inhibition aids in the differentiation of stem cells
• Hadley Brotz– Retrospective review of thromboprophylaxis in patients undergoing urological surgery
• Yvonne Kong– The role of Endoplasmic Reticulum stress in Platelet production
• Marcus Lombard-Final analysis of the Prospective Cohort Study on patients with a Haematological malignancy on Anticoagulants who develop Thrombocytopaenia (HAT Study).
• Hannah Stevens– Metabolomic Signatures as Predictors of Bleeding in Anticoagulant Therapy

2024 THANZ International Travel Grant

• Andy Sing Ong Tang (Sarawak General Hospital, Malaysia)- Congenital factor XIII deficiency: a disease not to be forgotten – real world experience from Malaysia

2023 THANZ International Travel Grant

• Jialin Qiao (Xuzhou Medical University, China)- MTH1 protects platelet mitochondria from oxidative damage and is essential for GPCR-dependent platelet function and thrombosis
  Below: Jialin recieving his certificate from THANZ President, Chee Wee Tan

2023 THANZ Travel Grant Winners

• Marc Ellis (John Lloyd Travel Grant) – GPIb-FilaminA interaction regulates megakaryocyte localization and budding during platelet biogenesis
• Yvonne Kong – Endoplasmic reticulum (ER) stress activation determines megakaryocyte and platelet ER chaperone distribution.
• Rowena Brook – Spontaneous bleeding in chronic kidney disease patients – global coagulation assays may be predictive of bleeding risk.
• Joanne So – Venous anomalies – an under-recognised but important cause of venous thromboembolism (VTE)
• David Capraro – Investigating the bidirectional interactions between platelets and colorectal cancer and the effects of aspirin
• Caroline Reddel – Age-related changes in overall haemostatic potential

2022 Inaugural THANZ International Travel Grant

• Dr Akbar Dorgalaleh (Iranian Comprehensive Hemophilia Care Center): The relationship between coagulation factor activity level and bleeding severity and quality of life in patients with rare bleeding disorders.

2022 THANZ Travel Grant Winners

• Christine Lee (JohnLloyd Grant): Procoagulant platelet assay for the diagnosis and monitoring of platelet-activating antibodies in vaccine-induced immune thrombotic thrombocytopenia (VITT) – Australian cohort’
• Lisa Clarke: Vaccine-induced Immune Thrombotic Thrombocytopenia post Dose 2 ChAdOx1 nCoV19 vaccination: less severe but not void of catastrophic outcomes
• Brian Grainger: Characteristics and outcomes of Australian adults with immune thrombocytopenia (ITP): the Melbourne Adult ITP (MA-ITP) Registry
• Helena Liang: Myeloproliferative neoplasm (MPN) patients show increased platelet mitochondrial mass with abnormal distribution and impaired mitochondrial function’
• Hannah Stevens: Novel Prothrombotic Genetic Variants, TSPAN15 rs78707713 and SLC44A2 rs2288904, are associated with an increased risk of Cancer-associated Thrombosis

2021 THANZ Conference Grant Winners

• Tina Noutos (John Lloyd Grant): Snakebite associated thrombotic microangiopathy in the Australian Snakebite Project
• Diane Lovelock: A curious case of heparin resistance
• Dianne Van der Wal: Storage of apheresis platelets in lipaemic plasma affects aspects of platelet function and surface receptor expression
• Julie Wang: Overall Haemostatic Potential identifies greater severity of COVID-19 infection
• Silvia Zheng: Anti-platelet Antibody’s Differential Impact in ITP

2019 THANZ Travel Grant Winners (Aus$1,000 each)

• Amandeep Kaur (John Lloyd Travel Grant): The ribosomal biogenesis inhibitor CX5461 is an anti-cancer therapeutic that increases platelet count in mice and in human
• Even Pennell: Acute bilirubin ditaurate exposure attenuates ex vivo platelet reactive oxygen species production, granule exocytosis and activation.
• Silvia Zheng: Anti-αIIbβIII autoantibodies induce platelet desialylation in immune thrombocytopenia
• Anneke Vanderham: Viper venom and algorithms: Lupus Anticoagulant Diagnosis in the days of the DOAC
• Joseph Rigano: Evaluation of DOAC-Stop® to Eliminate the Interference of Direct Oral Anticoagulants on Thrombophilia Assays
• Dianne Lovelock: Acquired Haemophilia A – a laboratory perspective

2018 THANZ Travel Grant Winners (Aus$1,000 each)

• Maria Selvadurai (John Lloyd Travel Grant):Targeting the platelet internal membrane reveals a novel approach for improved anti-platelet therapies
• David Rabolini: An Integrated Approach to Inherited Platelet Disorders: Results from a Research Collaborative, the Sydney Platelet Group
• James McFadyen: Compression force sensing regulates integrin αIIbβ3 adhesive function on diabetic platelets
• Yvonne Brennan: Lessons learnt from local real-life experience with idarucizumab for the reversal of dabigatran
• Helena Liang: Patients with coronary artery disease have increased circulating procoagulant platelets and appear primed to undergo loss of platelet mitochondrial integrity
• Caroline Reddel: Enhanced fibrinolysis and reduced microvesicles after remote ischaemic preconditioning in non-diabetic coronary artery disease patients

2017 THANZ Travel Grant Winners (Aus$1,000 each)

• Samantha Monague (John Lloyd Travel Grant): Fibrin-mediated GPVI shedding in patients with trauma or inflammation
• Jim Tio: miR-494-3p regulates transcription factors Sp1 and STAT5B to modulate haemostatic factor expression
• Dianne van der Wal: The role of platelet-attached glycans in platelet function
• Shauna French: A common protease-activated receptor 4 variant causes platelet hyper-reactivity and its blockade is antithrombotic
• Alyssa Rocchi: 2’OMe oligonucleotides block the miR-494/PROS1 interaction in patients with PS deficiencies
• Yusrah Harahsheh: Use of thromboelastography to identify patients with acquired coagulopathy at risk of developing thromboembolic events.

2016 THANZ Travel Grant Winners (Aus$1,000 each)

• Marie-Christine Kopp (John Lloyd Travel Grant): Identification of a new dysfunctional platelet P2Y12 receptor variant in a family with bleeding history
• Genia Burchall: Aberrant Haemostasis from OCP, but not Metformin use in Polycystic Ovarian Syndrome (PCOS)
• Hiu Lam Agnes Yuen: Venous Thromboembolism (VTE) in Patients with Primary Central Nervous System Lymphoma (PCNSL) Receiving R-MPV
• Jasmine Tay: Validation of plasma miR-494-3p and miR-365a-3p expression levels as indicators of thrombotic risk
• Lette Ginsberg: Diagnostic algorithm in Heparin Induced Thrombotic Thrombocytopenia (HITT): review of serotonin release assay results
• Yenna Chun: MYH9 disorders are not uncommon in Australia and New Zealand: results from a platelet next generation sequencing (NGS) project

2015 THANZ Travel Grant Winners (Aus$1,000 each)

• Shauna French (John Lloyd Travel Grant): Inhibition of the platelet thrombin receptor, PAR4, impairs platelet procoagulant function and is sufficient to provide an anti-thrombotic effect in human blood
• Win Lui: MicroRNA-494: a multifaceted regulator of coagulation
• Leonardo Pasalic: A whole blood assay using a novel cell death marker demonstrates procoagulant platelets are increased in patients with coronary artery disease with differential effects by anti-platelet therapy
• Jiayin Tian: Oestrogen sensitive microRNAs, a new player in regulating Factor VIII and tissue factor genes during pregnancy
• Scott McGregor: Comparative effects of rivaroxaban and apixaban on thrombin generation
• Marliesse Alexander: Biomarkers of thromboembolism in lung cancer

2014 THANZ Travel Grant Winners (AU $1000 each)

• Justin Hamilton (John Lloyd Travel Grant): PI3KC2a regulates platelet OCS structure and uncovers a novel link between the platelet internal membrane system, adhesive function and thrombus stability.
• Prahlad Ho: Thrombin generation in the normal population- Impact of age and sex
• Minh Hua: Platelet activation and procoagulant platelet formation appear to be uncoupled
• Susan Jarvis: Evaluation of Multiplate whole blood impedance aggregometry in routine investigation of bleeding disorders
• Prohan Lukito: Ventricular assist devices are associated with loss of platelet receptors
• James McFayden: Tractopods: Novel platelet membrane anchors promoting platelet-endothelial interactions and thrombo-inflammation

2013 THANZ Travel Grant Winners (Aus$1,000 each)

• James McFayden (John Lloyd Travel Grant): Tractopods are novel platelet glycoprotein IIbIIIa dependent adhesion strucures that are dysregulated in diabetes and chronic oxidative stress
• Vincent Chow: Enhanced Coagulation and Reduced Fibrinolytic Potential in Long-term Survivors of Pulmonary Embolism
• David Connor: The relationship between antiplatelet drug therapy and platelet microparticle formation and procoagulant activity in patients with cardiovascular disease
• Yusra Harahsheh: The Importance of Bethesda Assays in the diagnosis and monitoring of Thrombotic Thrombocytopenic Purpura (TTP) patients
• Minh Hua: Necrotic Platelets Play A Role in Occlusive Thrombi
• Louise Seymour: The KIR2DS5 genotype confers protection against adult Immune Thrombocytopenia

2012 THANZ Travel Grant Winners (Aus$1,000 each)

• Minh Hua (John Lloyd Travel Grant): Cell Death Imager- 1 Ligands in Apoptotic Platelets
• Ken Ly: Longitudinal Investigation of the Effect of Centrifugal Continuous Flow Left Ventricular Assist Devices (cfLVADS) on Haemostatic Parameters
• Gabrielle Pennings: Soluble EMMPRIN is associated with reduced coagulation potential in NSTEMI
• Carolyn Reddel: Increased Thrombin Generation in a Mouse Model of Cancer Cachexian
• Jasmine Tay: miR-494 Down regulates Protein S Expression
• Zane Kaplan: Directed Intravascular Leukocyte Migration: A Distinct Leukocyte Guidance Mechanism Mediated by Platelet Thrombi

2011 THANZ Trvel Grant Winners (Aus$1,000 each)

• Murray Adams: Impaired Control of the Tissue Factor Pathway in SLE
• Noel Chan: A Two-Centre (AUS-NZ) Retrospective Audit of Pregnancy Related Venous Thromboembolism (VTE): Failure of Current Guideline to Identify at Risk Patients in the Postpartum Period
• Tim Ganderton: Mechanism of Lateral Self-Association of Von Willebrand Factor
• Ming Hua: CDI-1 is a novel marker of platelet apoptosis
• Jian-Lin Qiao: Analysis of Platelet Receptor Expression in ITP
• Angus Wong: Development of a Microfluidic Device to Monitor Platelet Aggregation Dynamics and Function in the Context of von Willebrand Disease

2010 THANZ Travel Grant Winners (Aus$1000 each)

• Reanu Gopal: Thrombin Generation in Mild and Moderate Haemophilia A
• Eileen Merriman: Prothrombinex-VF for Reversal of Coagulopathy: Efficacy and Safety in Patients with Mechanical Heart Valves
• Jian-Lin Qiao: A Patient With Myelodysplastic Syndrome And An Acquired Defect In Platelet Response To Collagen Helps Redefine The Signalling Pathway Leading To GPVI Shedding
• Marc Ramsperger: Molecular characterisation of the immune response to Factor VIII (FVIII) in haemophilia A patients
• Caroline Reddel: Detection of Hypercoagulability in Coronary Artery Disease Patients using the Overall Haemostatic Potential (OHP) Assay: A Pilot Study
• Rajiv Subramanian: Hematological spectrum and Clinical Profile of Glanzmann Thrombasthenia in Southern India: Study of 221 patients from a tertiary centre

2009 THANZ Travel Grant Winners (Aus$1000 each)

• Steve Lazar: Understanding Hospital Physicians Perspectives and Attitudes towards the Implementation of Venous Thrombosis Prophylaxis
• Marie-Christine Morel-Kopp: Rapid diagnosis of heparin-induced thrombocytopenia by whole blood imdedance aggregometry
• Tina Noutsas: A Single Institution Experience with Retrievable Inferior Vena Caval Filters
• Chee Wee Tan: Lepirudin Use and Laboratory Monitoring in Patients on Chronic Haemodialysis with a history of Heparin-induced Thrombocytopenia(HIT)
• Natalie Tjen: Vancomycin induced thrombocytopenia in hospitalised patients
• Huy Tran: Thrombin Generation and Vitamin K Dependent Procoagulant Factors in Warfarinised Adult Patients

2008 THANZ Travel Grant Winners (Aus$1000 each)

• Murray Adams: The effect of Capsaicin and Dihydrocapsaicin on blood coagulation and platelet aggregation in vitro
• Kate Burbury: Warfarin Reversal, for Elective Surgical Procedures, Using Low Dose Intravenous Vitamin K: Impact on Vitamin K-Dependent Factor Levels
• Lisa Lincz: Endogenous Thrombin Potential (ETP) as a Novel Method for Characterization of Procoagulant Snake Venoms
• Deepak Singhal: A Report on Acquired haemophilia A in South Australia from 1998 to 2008
• Peter Tan: The Use of a Prothrombin-Complex Concentrate (Prothrombinex-VF®) in Medical and Surgical Patients – A Review of a Single Institution’s Experience
• Huy Tran: A single tertiary centre experience with inhibitors in paediatric patients with severe haemophilia

2007 THANZ Travel Grant Winners (Aus$1000 each)

• Christina Brown: Influence of lepirudin and warfarin on APTT, Ecarin Clotting Time and INR: Implications for laboratory monitoring of patients with heparin induced thrombocytopenia
• David Connor: Phospholipid-dependent Procoagulant Activity of Platelet-derived Microparticles is Restricted to the Annexin V Binding Subpopulation
• Jenny Curnow: Reduced Fibrinolysis and Increased Fibrin Generation is seen in Patients with Thrombotic Complications of Pregnancy Compared with Normal Pregnancy
• Caroline Moraes: A Rapid Automated Technique to Detect Platelet Activation in Plasma
• Beatrice Mui: Platelet Function Testing using a modified cone and plate assay on the Diamed Impact-R
• Helen Weston: Comparison of the PFA-100 Assay with Von Willebrand Testing in the Laboratory Assessment of Response to DDAVP in Coagulation and Platelet Disorders

2006 TANZH Travel Grant Winners (Aus$1000 each)

• Vanessa Cole: The molecular characterisation of a proteini S deficient pedigree
• Ashley Ng: A review of TTP at the Royal Melbourne Hospital
• Lay Tay: A comparative study of different methods of monitoring LMWH

2005 THANZ Travel Grant Winners (Aus$750 each)

• Dolly Daniel: International normalised ratios measured at home with a point of care device diverge from hospital laboratory results when starting Warfarin
• Emma Perrin: A comparison of Enoxaparin and unfractionated Heparin in combination with Tirofiban during percutaneous coronary intervention: Effects on inhibition of coagulation and activation of platelets
• Linda Saravanan: Afibrinogenaemia due to a compound heterozygosity for two termination events in the Aα chain

2004 THANZ Travel Grant Winners (Aus$1000 each)

• Karen Allan: Activated seven lupus anticoagulant method development
• Murray Adams: The tissue factor pathway in ischaemic stroke patients
• Kate Maslen: Measurement of soluble P – selectin and soluble CD40 ligand in serum and plasma